Table 1.

—The Clinical Characteristics of Individuals With HIV Infection and Lung Cancer

Study	Study Period	Sample Size	No. With Lung Cancer	Average Age, y	Male Sex, %	Smoker, %	IVDU, %	cART, %	CD4 Count, cells/μL	Histology (% of Total)	Stage (% of Total)	Survival, mo
Karp et al10	1983-1991	205	7	38	86	100	100	0	N/A	Adeno (100)	IV (100)	1
Sridhar et al11	1986-1991	1,336	19	47	100	N/A	21	0	121	Adeno (42)	IV (58)	3
Alshafie et al2	1990-1994	127	11	50	82	90	82	N/A	329	Adeno (45)	IV (45)	3
Vyzula and Remick12	1988-1995	N/A	16	45	94	N/A	63	0	184	Adeno (50)	N/A	5.4
Parker et al13	1990-1995	26,181	36	49	97	N/A	N/A	0	N/A	Adeno (33)	IIIB/IV (89)	N/A
Tirelli et al14	1986-1998	138	36	38	89	N/A	69	8	150	Adeno (42)	IV (55)	5
Bower et al15	1986-2001	8,400	11	45	91	N/A	N/A	55	160	Adeno (45)	IV (54)	2
Spano et al16	1993-2002	N/A	22	45	86	N/A	23	N/A	364	Squamous(50)	III/IV (75)	7
Powles et al17	1996-2002	36	9	45	N/A	N/A	N/A	N/A	160	Adeno(66)	IV (66)	4
Engels et al18	1989-2003	5,238	33	46	67	69	57.5	57.1	> 200	Adeno(48)	N/A	N/A
Hakimian et al19	1996-2003	N/A	34	44	68	N/A	86	60	> 200	NSCLC (88)	IV (53)	8.2
Brock et al20	1986-2004	5,065	92	46	67	89	58	62	305	Adeno (48)	IV (69)	6.3
Lavolé et al21	1996-2007	5,170	49	46	86	N/A	35	73	350	Adeno (67)	III/IV (84)	8.1
Bertolaccini et al22	2003-2007	N/A	26	39	85	N/A	58	85	143	NSCLC (81)	IV (33)	23
Pakkala et al23	1995-2008	N/A	80	52	80	N/A	25	55	304	Adeno (38)	IV (49)	6.1
D’Jaen et al24	1996-2008	36,569	75	50	83	76	30	80	340	Adeno (46)	IIIB/IV (77)	9
Engsig et al25	1995-2009	5,053	29	57	93	71	10	69	299	Squamous (28)	N/A	2
Ruiz26	2002-2009	2,060	16	49	69	N/A	N/A	100	211	Adeno (67)	IIIB/IV (85)	N/A
Clifford et al27	1985-2010	405	68	50	79	73	37	74	N/A	Adeno (32)	N/A	N/A

Adeno = adenocarcinoma; cART = combination antiretroviral therapy; IVDU = IV drug use; N/A = not available; NSCLC = non-small cell lung cancer.