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Public sector-recommended ART regimens according to the 2004 and 2010 South African National Treatment Guidelines
| Regimen | 2004 Guidelines | 2010 Guidelines |
|---|---|---|
| Drugs | Drugs | |
| First-line | d4T/3TC/EFV | TDF/3TC or FTC/EFV |
| Alternative first-line | d4T/3TC/NVP | TDF/3TC or FTC/NVP |
| Second-line | AZT/ddI/LPVr | AZT/3TC/LPVr |
3TC: lamivudine, AZT: zidovudine, ddI: didanosine, d4T: stavudine, FTC: emtricitabine, EFV: efavirenz, LPVr: lopinavir–ritonavir, NVP: nevirapine and TDF: tenofovir.
