Figure 4.
VEGFR-3 increases viability of breast cancer cells. (A) MTS assay (24 h) of MCF7-VEGFR-3 and MCF7-pcDNA3 cells. Viability was normalized relative to MCF7-pcDNA. (B) BT474 cells viability measured 24 h after pretreatment for 48 h with 10 nM VEGFR-3-specific and Control siRNAs. Viability normalized relative to untreated BT474 cells. (C) Viability of MCF7-VEGFR-3 cells in comparison to clones with VEGFR-3 shRNA knockdown, normalized relative to parental clone. (D) Viability of BT474 cells in comparison to clones with VEGFR-3 shRNA knockdown, normalized relative to parental clone.