Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
RNAi knockdown of VEGFR-3 expression in breast cancer cells reduces tumor growth
| Cell line stable clone | Median tumor volume (mm3) | Cell line stable clone | Median tumor volume (mm3) |
|---|---|---|---|
| MCF7-VEGFR-3 | 1204.5 ± 695.7 | BT474 | 2141.2 ± 428.3 |
| shCTL | 443.25 ± 91.2 | shCTL | 1649.7 ± 901.6 |
| shRNA1 | 34.575 ± 7.8 | shRNA1 | 849.6 ± 241 |
| shRNA2 | 32.225 ± 19.7 | shRNA2* | 1682 ± 967.9 |
BT474 clone shRNA2 express VEGFR-3 at the same level as parental BT474 and shCTL (control) cell lines (Fig. 2E).
