Figure 4. Effects of test compounds on drug discrimination (top), response rate (middle), and head shaking (bottom) in Δ9-THC (1 mg/kg/12 h s.c.) treated monkeys discriminating rimonabant (1mg/kg i.v.).
Abscissae: vehicle or dose of test compound in mg/kg body weight. Ordinates: mean (± S.E.M.) percentage of responding on the rimonabant lever (top), mean (± S.E.M.) response rate expressed as a percentage of control (VEH training days) rate [Rate (% Control)] (middle), and head shaking frequency in 40 min (bottom). The control data (closed circles) in the top and middle panels are re-plotted from Figure 1. Symbols represent mean (± S.E.M.) values from each of 4–5 monkeys.