Table 1. Secretory pathway components shown to associate with RNAs.
Protein Name | Annotated Function* | Annotated Localization* |
---|---|---|
Sec1# |
Docking and fusion of exocytic vesicles |
Bud neck; bud tip |
Sec16# |
COPII vesicle coat component; transport of ER vesicles |
COPII vesicle |
Sec31# |
COPII vesicle coat component; transport of ER vesicles |
COPII vesicle |
Sec26# |
COPI vesicle coat component; ER-to-Golgi transport |
COPI vesicle |
Sec27# |
COPI vesicle coat component; ER-to-Golgi transport |
COPI vesicle |
Ubp3# |
Ubiquitin-specific protease; ER-Golgi anterograde and retrograde transport |
Cytosol |
Vtc1# |
Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking |
Vacuole; ER |
Ypt1#,‡ |
Rab family GTPase; ER-to-Golgi step of the secretory pathway |
ER and Golgi |
Ypt7‡ |
Rab family GTPase; late endosome-to-vacuole sorting |
Vacuole |
Ypt32‡ |
Rab family GTPase; trans-Golgi-to-plasma membrane sorting |
Endosome and Golgi |
Rho3‡ | Rho/Rac GTPase; establishment of cell polarity | Cytosol; cell bud; plasma membrane |
Data from the Saccharomyces genome database (www.yeastgenome.org); #Data from Tsvetanova NG, Klass DM, Salzman J and Brown PO (2010); associated with total mRNA; ‡Data from Tsvetanova NG, Riordan DP and Brown PO (2012); associated with HAC1 RNA