Table 4. Adipogenesis differentiation pathway.
Genotypes/Alleles | Controls n (%) | Cases n (%) | p-value | OR (95% CI) |
SREBP2 1784G>C | ||||
GG | 145 (65.9) | 138 (60.0) | − | 1 (reference) |
GC | 73 (33.2) | 82 (35.7) | 0.475 | 1.16 (0.77–1.74) |
CC | 2 (0.9) | 10 (4.3) | 0.045 | 4.87 (1.03–22.96) |
Ptrend | 0.067 | |||
*MCS | 0.057 | |||
GC+CC | 75 (34.1) | 92 (40.0) | 0.250 | 1.26 (0.85–1.87) |
G | 363 (82.5) | 358 (77.8) | − | 1 (reference) |
C | 77 (17.5) | 102 (22.2) | 0.165 | 1.27 (0.91–1.79) |
PPARG γ2 C>G | ||||
CC | 178 (80.9) | 176 (76.5) | − | 1 (reference) |
CG+GG | 42 (19.1) | 54 (23.5) | 0.351 | 1.25 (0.78–1.98) |
Ptrend | 0.256 | |||
*MCS | 0.218 | |||
C | 398 (90.5) | 406 (88.4) | − | 1 (reference) |
G | 42 (9.5) | 54 (11.6) | 0.652 | 1.11 (0.71–1.72) |
MCS = Monte Carlo Simulation; Significant values are in bold; For categorical data Cochrane Armitage trend test was used.