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. 2013 Apr 8;8(4):e60715. doi: 10.1371/journal.pone.0060715

Figure 1. PPAR δ knockdown promoted the growth of xenografts in nude mice.

Figure 1

(A). Growth curve of xenografts. At each time point, the xenografts in PPAR δ-silenced group (n = 12) grew significantly larger than those of control group (n = 12) (*P<0.05), even when treated by bevacizumab (**P<0.05) (mean±SD, t-test). (B). Representative photograph of mice in each group was taken 25 days after inoculation. (C). The xenografts when nude mice sacrificed. (D) The xenografts in PPAR δ-silenced group were significantly heavier than those in control group when nude mice sacrificed (mean±SD; *P = 0.021; **P = 0.02; t-test).