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. 2013 Apr 8;8(4):e60715. doi: 10.1371/journal.pone.0060715

Figure 2. PPAR δ knockdown induced less differentiation of xenografts.

Figure 2

(A). Representative photographs of xenografts by HE staining. The xenografts in PPAR δ-silenced group (n = 12) were obviously less-differentiated than those in control group (n = 12).×400 magnification. (B). PPAR δ- silenced group had significantly more less-differentiated xenografts than control group (85% vs. 17%, P = 0.025; Chi-square test). (C). Shown by quantitative RT-PCR, the mRNAs encoding ADRP, L-FABP or ALPI were significantly decreased in PPAR δ-silenced group relative to control group (P<0.05).