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Groups of mice were infected intracranially (A, B) or intraperitoneally (C) with the indicated dose of MHV-nsp1-27D or MHV-A59. The survival rates of mice were monitored daily. For mice infected intraperitoneally with 5×106 pfu of MHV-nsp1-27D or MHV-A59 (C), the animal weight was monitored daily. Each time point represents the mean data from at least five individual mice.
