Figure 4. The persistent global bias has a strong impact on the final states of Model A.

(A) Initial condition with a strong polarity of Dsh and Vang in the direction opposite to the direction of the final state observed in experiments. Pk and Fz are initially distributed homogeneously; (B) final state for a global bias of and the parameter values in Table S1; (C) final state for a global bias of , the parameter values in Table S1 but with no feedback (i.e. ). Even without feedback the cells polarise correctly, albeit more weakly than with feedback.