Table 1. Clinical Characteristics of the 4 Study Groups.
| GROUPS | 1 | 2 | 3 | 4 | |
| Recurrent Events (n = 25) | Single Remote MI (n = 25) | Longstanding AlwaysStable CAD (n = 25) | No CAD (n = 25) | ||
| Age (years) | 65.6±8.4* | 64.6±7.2 | 66.3±6.4 | 61.2±8.0 | |
| Sex (male) | 88% (22)† | 84% (21) | 88% (22) | 72% (18) | |
| BMI (kg/m2) | 29.9±4.1 | 28.6±3.0 | 28.4±3.4 | 29.4±5.2 | |
| BMI >30 | 52% (13) | 28% (7) | 28% (7) | 38% (9) | |
| Waist circumference (cm) | 103.7±10.7 | 98.4±10.4 | 99.2±11.5 | 96.3±12.7 | |
| Current smoker | 28% (7) | 12% (3) | 16% (4) | 12% (3) | |
| Ex-smoker | 60% (15) | 72% (18) | 56% (14) | 60% (15) | |
| Never smoker | 12% (3) | 16% (4) | 28% (7) | 28% (7) | |
| Type 2 diabetes | 32% (8) | 16% (4) | 28% (7) | 0% | |
| Hypertension | 80% (20) | 48% (12) | 72% (18) | 52% (13) | |
| Dyslipidemia | 100% (25) | 96% (24) | 96% (24) | 36% (9) | |
| 1st cholesterol value (mmol/L) | 3.81±0.94 | 3.94±0.47 | 3.96±0.72 | 4.79±0.94 | |
| History of renal failure | 8% (2) | 0% | 4% (1) | 4% (1) | |
| Serum creatinine (µmol/L) | 89.2±24.6 | 88.9±24.7 | 83.2±16.8 | 80.5±11.7 | |
| Urinary albumin/creatinine ratio | 25.7±33.5 | 7.4±9.7 | 28.7±35.2 | 12.5±23.1 | |
| History of heart failure | 32% (8) | 0% | 0% | 0% | |
| LV ejection fraction (%) | 46±12 | 54±9 | 64±7 | 62±5 | |
| Duration CAD (years) | 19.0±10.1 | 12.0±4.4 | 16.7±7.9 | – | |
| Stroke/TIA | 4% (1) | 0 | 4% (1) | 0 | |
| Peripheral arterial disease | 20% (5) | 0 | 12% (3) | 0 | |
| Ankle/brachial index | 1.1±0.4 | 1.2±0.2 | 1.2±0.3 | 1.2±0.1 | |
| Medications | |||||
| Lipid-lowering drugs | 96% (24) | 96% (24) | 92% (23) | 40% (10) | |
| Angiotensin modulators | 72% (18) | 44% (11) | 36% (9) | 8% (2) | |
| Beta-blockers | 88% (22) | 68% (17) | 72% (18) | 28% (7) | |
| Aspirin/antiplatelet drugs | 96% (24) | 100% (25) | 96% (24) | 44% (11) | |
*
± refers to standard deviation values;
†
numbers of subjects in parentheses; MI = myocardial infarction; CAD = coronary artery disease; BMI = body mass index; LV = left ventricular; TIA = transient ischemic attack.