Table 5. Multivariable Cox regression analysis^* for the risk of death (OS) in node-positive breast cancer patients.

	Univariate Cox-Regression		Multivariable Cox-Regression
Variable	HR (95% CI)	p	HR (95% CI)	p
HTRA1expression (low/high)	0.21 (0.07–0.63)	0.006	0.25 (0.08–0.80)	0.020
Tumor stage (pT1+2/pT3+4)	2.51 (0.93–6.78)	0.070	1.44 (0.48–4.31)	0.511
Adjuvant therapy (no/yes)	0.33 (0.12–0.928)	0.036	0.54 (0.18–1.64)	0.277

^*Number of patients in multivariable analysis: n = 60; number of events of death: 18; binary variables are used; HR, hazard ratio; 95% CI, 95% confidence interval; OS, overall survival with endpoint death of any cause.