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. 2013 Apr 8;210(4):683–697. doi: 10.1084/jem.20121798

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© 2013 Van de Walle et al.

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Figure 2. — Jagged1 fails to support DP differentiation from mouse thymocytes. Flow cytometric data of murine c-kit⁺ fetal thymocytes after 7 or 10 d of coculture on OP9 stromal cells that express different Notch ligands (as indicated above dot plots). Early DN stages are distinguished by expression of CD44 and CD25 (top row) and T cell maturation is monitored by the coexpression of CD4 and CD8 (middle row). Development of TCR-γδ⁺CD3⁺ cells is shown in the bottom row. Results shown are representative of three independent experiments.