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. 2013 Apr 8;210(4):821–838. doi: 10.1084/jem.20122005

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© 2013 D’Antonio et al.

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Figure 2. — The lipid/cholesterol biosynthetic program is strongly down-regulated in S63del nerves. (A) L2L analysis at P5 of genes down-regulated in S63del nerves identified an enrichment for GO categories related to lipid metabolism. (B) Quantitative RT-PCR for a selection of enzymes involved in the cholesterol biosynthetic pathway. Error bars, SEM; n = 4 RT from independent pools of nerves. *, P < 0.05, **, P < 0.01 by Student’s t test; n.s. = not significant.