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. 2013 Apr 8;8(4):e61288. doi: 10.1371/journal.pone.0061288

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© 2013 Bose et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Comparative anti-hCG immunoglobulin isotypic analysis of antibodies in five murine strains immunized with βhCG-TT and βhCG-TT + MIP. (A) BALB/c; (B) FVB/J; (C) C57BL/6; (D) CBA/Cat; (E) C3H/HeJ. Relative Units: Relative end-point titres. Pre-immune sera served as control. (F) Fold-increases in hCG specific IgG1, IgG2a and IgG2b antibody isotypes in different strains upon the inclusion of MIP in the vaccine formulation.