Table 3.
Renal Interstitial Inflammatory Cell Infiltrates
| Toxin | Dose ng/kg (No.) | Survival, average hours (range) | Mono (Range, 0–4) | Poly (Range, 0–4) |
|---|---|---|---|---|
| Stx1 | 10 (3) | 168∗ | 0 (0) | 0 (0) |
| 50 (5) | 69 (58–168) | 0.20 (0–1F) | 0.6 (0–2FE) | |
| 100 (5) | 57.4 (48–72) | 0 (0) | 0 (0) | |
| Stx2 | 10 (4) | 153.8 (111–168) | 1.5 (0–2F) | 1.0 (0–2FE) |
| 50 (7) | 108.4 (84–128) | 0.42 (0–2F) | 1.3 (0–2FE) |
E, infiltrate includes eosinophils; F, focal (otherwise diffuse); Mono, mononuclear; Poly, polymorphonuclear.
Animal survived to day 7 (necropsy at approximately 168 hours).