Table 2.

BM Chimera EAE Clinical Disease Characteristics

Donor listed first, recipient second	Average day disease onset	Average maximum disease score	Sum daily average disease score	Disease index	Percent mortality
WT→WT	13.92	2.73†††	105.2	755.6†††	7.00
CD44-KO→WT	12.88	4.09∗∗††	163.9	1273.3∗∗††	18.75
WT→CD44-KO	13.67	3.80∗†	151.2	1106.7∗††	31.25
CD44-KO→CD44-KO	12.06	4.75∗∗∗	212.2	1758.69∗∗∗	68.75

EAE disease measurements from BM chimeric mice.

∗P < 0.05, ∗∗P < 0.005, and ∗∗∗P < 0.0001 versus WT→WT.

^†P < 0.006, ^††P < 0.0004, and ^†††P < 0.0001 versus KO→KO.