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| Topoisomerase Target | IC50 for Inhibition of catalytic activity | Poison Inhibitor Mechanism |
| E. coli and Y. pestis Topo I (Type IA) | 14–19 µM | Yes |
| E. coli DNA gyrase Type IIA) | 19 µM | No |
| Human Topo I (Type IB) | 230 µM | No |
| Human Topo Iiα (Type IIA) | 35 µM | Yes |
