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(A) Representative H&E-stained lung sections from saline and nicotine-exposed animals at postnatal day 1 (PND1), 3 and 12 weeks of age. (B) Mean linear intercept in the lungs of male rats exposed to saline (closed circles) or nicotine (open circles) during fetal and neonatal life. Data are presented as mean ± SEM. Values marked with an asterisk (*) are significantly different (p<0.05) from the saline controls at the same age.
