Table 1.
Antitumor activities of the isolated compounds on the proliferation of different cell lines
|
Compound |
Inhibitory Rate for Different Cell Lines (%, mean ± SD)a |
||||
|---|---|---|---|---|---|
| MGC-803 | PC3 | A549 | MCF-7 | NIH3T3 | |
|
β-sitosterol (1) |
23.5 ± 2.1 |
16.5 ± 2.3 |
12.6 ± 3.1 |
18.9 ± 1.7 |
5.6 ± 2.4 |
|
α-Amyrin (2) |
23.5 ± 5.4 |
17.8 ± 4.9 |
7.8 ± 1.5 |
10.4 ± 1.8 |
7.6 ± 4.5 |
| Daucosterol (3) |
12.3 ± 4.1 |
9.8 ± 3.6 |
4.5 ± 1.8 |
7.2 ± 5.2 |
4.3 ± 2.3 |
| Quercetin (4) |
17.2 ± 1.7 |
22.7 ± 1.4 |
16.9 ± 2.4 |
42.2 ± 1.6 |
4.2 ± 2.5 |
| (+)-Catechin (5) |
52.1 ± 5.7 |
49.6 ± 2.3 |
45.3 ± 3.2 |
37.6 ± 3.9 |
28.9 ± 4.3 |
| (−)-Epicatchin (6) |
45.5 ± 4.1 |
50.6 ± 1.6 |
47.1 ± 1.1 |
43.2 ± 3.6 |
22.5± 3.8 |
| Kampferol (7) |
58.2 ± 3.0 |
46.1 ± 5.9 |
42.0 ± 2.2 |
39.2 ± 6.8 |
11.1 ± 6.7 |
| 3-Oxours-12-en-28-oic acid (8) |
45.2 ± 2.0 |
42.5 ± 1.4 |
35.9 ± 0.8 |
37.2 ± 1.5 |
23.6 ± 1.3 |
| Ursolic acid (9) |
52.1 ± 2.2 |
55.6 ± 2.4 |
37.6 ± 1.7 |
47.8 ± 1.2 |
21.7 ± 4.9 |
| Betulonic acid (10) |
56.1 ± 2.6 |
63.4 ± 4.2 |
35.2 ± 2.4 |
51.2 ± 4.4 |
22.1 ± 6.2 |
| Gallic acid (11) |
55.7± 1. 9 |
40.2 ± 4.2 |
46.3 ± 3.6 |
33.1 ± 1.4 |
13.6 ± 2.2 |
| Betulinic acid (13) |
36.9 ± 1.6 |
23.6 ± 3.4 |
33.5 ± 2.3 |
41.6 ± 3.7 |
23.4 ± 2.9 |
| ADM | 92.1 ± 1.3 | 93.4 ± 2.6 | 96.2 ± 0.8 | 91.1 ± 2.2 | 99.4 ± 0.4 |
Note: a Inhibitory percentage of cells treated with each compound 20 μmol/L for 72 h and SD = standard deviation.