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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: J Immunol. 2013 Jan 30;190(5):2282–2291. doi: 10.4049/jimmunol.1201215

Fig.6. Autocrine type I interferons are required for the ability of A.a.-infected DCs to stimulate type I NKT cells.

Fig.6

A. Murine BMDCs were infected with A.a. (MOI 10) with or without blocking mAb against IFNaR, or mouse IgG1 isotype control, or left uninfected. 24 h later, liver MNCs were added with or without anti-IFNaR mAb or isotype controls. Data shown are representative of three experiments. B. BM-DC of WT and IFNAR knockout mice were infected with A.a. (MOI 10) or left untreated (n=3). IFN-γ levels in supernatants (48h) were assessed by ELISA. * p<0.05;**, p<0.01; ***, p<0.001; n.d, not detectable; n.s, not significant.