Figure 6.

mPA‐ZHER2‐mediated killing in a heterogeneous cell population. Tumor cells were plated in separate compartments of a chambered slide (right panel) and incubated at 37 °C. The following day, the chambers were removed, and the slide was incubated with mPA‐ZHER2 plus LFN‐DTA. After 4 h, cells were incubated with medium supplemented with [3H]‐leucine for 1 h and dissolved in 6 M Guanidine–HCl, and the incorporated radiolabel was quantified by scintillation counting. Percent protein synthesis was normalized against cells treated with mPA + LFN‐DTA.