Table 3.

Discriminatory Power of Models for Predicting Severe Obstructive Sleep Apnea Syndrome^a

Single‐Stage Model	Cutpoint	SENS	SPEC	Neg LR	NPTP
NC, cm	42.550	0.856	0.510	0.244	0.017
Morphometrics	79.998	0.669	0.701	0.473	0.006
MVAP	0.483	0.915	0.439	0.190	0.015
BMI, kg/m2	30.937	0.819	0.505	0.334	0.018
Symptoms	1.000	0.774	0.551	0.394	0.035
Age, y	48.275	0.629	0.299	1.641	0.029

Two‐Stage Model	LB	UB	HST Cutpoint	SENS	SPEC	Neg LR	NPTP
NC, cm	40.65	46.55	23.5	0.836	0.770	0.212	0.020
Morphometrics	40	95	23.25	0.942	0.689	0.076	0.037
MVAP	0.41	0.79	18	0.882	0.716	0.162	0.015
BMI, kg/m2	25	41.25	23.75	0.829	0.708	0.219	0.027
Symptoms	1.2	3.1	20	0.629	0.840	0.442	0.031
Age, y	32.5	65	15.25	0.743	0.694	0.368	0.119

Abbreviations: BMI, body mass index; HST, home sleep testing; LB, lower bound; MVAP, Multivariable Apnea Prediction Score; NC, neck circumference; NegLR, negative likelihood ratio; NPTP, Negative post‐test probability; SENS, sensitivity; SPEC, specificity; uAHI, Apnea‐Hypopnea Index (AHI) from unattended home sleep test; UB, upper bound.

^aSevere obstructive sleep apnea syndrome=AHI ≥30 events/h + Epworth Sleepiness Scale >10.