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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Immunol Rev. 2013 May;253(1):65–81. doi: 10.1111/imr.12061

Fig. 3. Interplay of miRNA expression and 3′UTR usage shapes genetic networks.

Fig. 3

Schematic representation of an extracellular cue (e.g. cytokine) on a T cell and its consequence on the genetic network. (A) A cytokine induces a network of genes A–M. (B) miRNA expression allows to shape the gene expression program induced by the cytokine. (C) The interplay of miRNA expression and alternative polyadenylation (APA) provides a cell additional flexibility to respond to the cytokine.