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. Author manuscript; available in PMC: 2013 Apr 9.
Published in final edited form as: Cancer Res. 2008 Jun 15;68(12):4606–4613. doi: 10.1158/0008-5472.CAN-07-5046

Figure 6.

Figure 6

Immunochemical analysis of serial sections from paired primary ovarian tumors and metastatic lesions. Serial sections of (A) primary serous ovarian tumor samples and (B) paired peritoneal metastases were stained with antibodies to active (phospho-) EGFR, MMP-9, or E-cadherin (as indicated) and scored as described in “Materials and Methods”. MMP-9 expression was high in all phospho-EGFR positive metastases, while the majority concomitantly exhibited decreased E-cadherien staining relative to the paired primary tumor. 400× magnification.