Table 2.
Unadjusted analysis of first IVF cycle characteristics and outcomes for fertility preservation patients and matched controls.
| Cases (n = 50) | Controls (n = 50) | P-value | |
|---|---|---|---|
| Baseline oestradiol (pg/ml)a | 48.1 (40.9–56.8) | 39.2 (35.5–13.4) | 0.040 |
| Baseline FSH (mIU/ml)a,b | 5.3 (4.3–6.7) | 5.7 (5.1–6.4) | NS |
| Baseline AMH (ng/ml)a,c | 2.0 (1.6–2.8) | 2.5 (1.5–4.1) | NS |
| Baseline antral follicle count | 21.1 (17.6–24.7) | 19.4 (16.8–22.0) | NS |
| Days of stimulation | 9.9 (9.2–10.5) | 10.1 (9.6–10.6) | NS |
| Starting gonadotrophin dose (IU) | 281.2 (247.5–315.0) | 238.8 (204.8–272.7) | NS |
| Total gonadotrophin dose (IU) | 3009 (2573–3444) | 2556 (2079–3033) | NS |
| Total follicle number | 21.6 (18.2–25.1) | 22.8 (19.4–26.1) | NS |
| Total follicles >14 mm | 11.1 (9.5–12.7) | 11.8 (10.6–12.9) | NS |
| Oestradiol at trigger (pg/ml)a | 933 (709–1228) | 2730 (2453–3044) | <0.001 |
| Endometrial thickness at trigger (mm) | 9.6 (8.7–10.4) | 10.6 (9.8–11.4) | NS |
| No. of oocytes retrieved | 12.4 (10.1–14.7) | 11.7 (10.1–13.3) | NS |
| No. of oocytes mature (M2) | 9.0 (7.4–10.5) | 8.9 (7.6–10.2) | NS |
| No. of immature (GV + M1) | 2.2 (1.2–3.3) | 1.1 (0.6–1.5) | 0.030 |
| Maturation rate | 74.1 (67.6–80.6) | 76.7 (69.2–84.3) | NS |
| No. of 2PN embryos | 5.4 (4.1–6.6) | 6.0 (4.9–7.2) | NS |
| Fertilization rate | 51.6 (43.4–59.5) | 69.5 (60.8–78.3) | 0.002 |
Values are mean (95% CI).
a
Geometric mean presented.
b
Data available for 42 cases and 46 controls.
c
Data available for 27 cases and 14 controls.
AMH = anti-Mullerian hormone; NS = not statistically significant.