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. 2004 Mar 15;113(6):895–904. doi: 10.1172/JCI19852

Figure 8.

Figure 8

Protection against liver failure by chronic SAM treatment or antioxidants. (A) ASMase+/+ mice treated with Gal/LPS were administered SAM for 16 or 24 hours, and liver damage was assessed by serum transaminase analyses. Data are the mean ± SD of ten individual experiments. *P = 0.05 versus Gal/LPS. (B) Alternatively, ASMase+/+ mice were treated with NAC instead of SAM to analyze its effect on liver injury induced by Gal/LPS, as assessed by serum transaminases. Data are the mean ± SD of four individual experiments. *P = 0.05 versus Gal/LPS.