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. 2013 Jan 15;121(3):339–344. doi: 10.1289/ehp.1205582

Table 1.

Formaldehyde inhalation exposure in nonhuman primates significantly disrupts the expression levels of 13 unique miRNAs, represented by 15 array probesets.

miRNA Agilent array feature number 2 ppm formaldehyde 6 ppm formaldehyde
log2FC p-Value q-Value log2FC p-Value q-Value
miR-125b 2637 0.44 6.1 × 10–1 0.666 2.86* 2.2 × 10–4 0.090
miR-152 1548 0.79 3.0 × 10–3 0.297 1.29* 1.3 × 10–4 0.072
miR-219-5p 1180 0.36 8.8 × 10–2 0.451 1.22* 1.7 × 10–4 0.075
miR-532-5p 1259 0.35 3.4 × 10–2 0.390 1.09* 8.1 × 10–5 0.055
miR-520f 14457 –0.61 3.3 × 10–4 0.188 –0.77* 1.4 × 10–4 0.072
miR-26b 12607 –1.13 9.3 × 10–5 0.146 –1.38* 5.2 × 10–5 0.050
miR-140-5p 12026 –0.69 3.6 × 10–4 0.188 –1.56* 2.4 × 10–5 0.036
miR-22 12927 –0.69 4.8 × 10–4 0.203 –1.70* 2.6 × 10–5 0.036
miR-374a 14431 –1.68 1.2 × 10–4 0.148 –1.77* 1.1 × 10–4 0.067
miR-203 12162 –1.98* 4.7 × 10–5 0.098 –2.11* 4.1 × 10–5 0.046
miR-203 11451 –1.75 1.0 × 10–4 0.146 –2.12* 6.7 × 10–5 0.055
miR-142-3p 12366 –4.12* 1.1 × 10–6 0.009 –2.92* 1.6 × 10–6 0.011
miR-29a 13448 –3.24 2.5 × 10–4 0.188 –3.15* 2.6 × 10–4 0.099
miR-145 15649 –3.15* 3.0 × 10–5 0.098 –3.56* 2.6 × 10–5 0.036
miR-142-3p 14658 –2.81 3.1 × 10–4 0.188 –5.01* 1.8 × 10–4 0.075
FC, fold change. *p < 0.01, q < 0.1 for FC relative to unexposed samples.
HHS Vulnerability Disclosure