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. 2013 Jan 15;121(3):359–366. doi: 10.1289/ehp.1205701

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Transgenerational effects of DMSO (vehicle), ROSI, or TBT (5.42, 54.2, or 542 nM) on markers of hepatic lipid metabolism in F1, F2, and F3 male (A) and female (B) mice. Relative mRNA levels of PPARγ2, SREBP1c, GyK, and FASN (lipogenic markers); PPARα and ACOX (lipolytic markers); and Fsp27 and FATP (lipid droplet markers) were evaluated in total RNA from mouse liver. Data are expressed as mean fold change ± SEM of three biological replicates assayed in duplicate. *p < 0.05, **p < 0.01, and ^#p < 0.001 compared with DMSO vehicle by unpaired t-test.