Table 2.
Grading the severity of each parameter using Kleiner’s score[1]
| Score | |||
|---|---|---|---|
| Steatosis |
Grade |
<5% |
0 |
| 5–33% |
1 |
||
| 33–66% |
2 |
||
| >66% |
3 |
||
| Location |
Zone 3 |
0 |
|
| Zone 1 |
1 |
||
| Azonal |
2 |
||
| Panacinar |
3 |
||
| Microvesicular steatosis |
Not present |
0 |
|
| Presented |
1 |
||
| Fibrosis stage |
|
None |
0 |
| Perisinusoidal or periportal |
1 |
||
| Perisinusoidal and periportal/periportal |
2 |
||
| Bridging fibrosis |
3 |
||
| Cirrhosis |
4 |
||
| Inflammation |
Lobular inflammation |
No foci |
0 |
| <2 foci per 200× field |
1 |
||
| 2–4 foci per 200× field |
2 |
||
| >4 foci per 200× field |
3 |
||
| Liver cell injury |
Ballooning |
None |
0 |
| Few balloon cells |
1 |
||
| Many cells/ prominent ballooning |
2 |
||
| Acidophil bodies |
None to rare |
0 |
|
| Many |
1 |
||
| Pigmented macrophages |
None to rare |
0 |
|
| Many |
1 |
||
| Other findings |
Mallory's hyaline |
None to rare |
0 |
| Many |
1 |
||
| Glycogenated nuclei |
None to rare |
0 |
|
| Many | 1 |