Table 1.
Treatment group | Body weight (g) | Tumor volume (mm3) | Injected activity (MBq) | IA/kg body weight (MBq/kg) |
---|---|---|---|---|
Controls (unlabeled BR96) |
|
|
|
|
Tumor (n = 6) |
290 (282 to 300) |
520 (282 to 640) |
- |
- |
Non-tumor (n = 3) |
289 (281 to 296) |
- |
- |
- |
2.5 MBq 211At-BR96 |
|
|
|
|
Tumor (n = 6) |
272 (269 to 278) |
475 (256 to 640) |
2.5 (2.5 to 2.6) |
9.3 (9.0 to 9.6) |
Non-tumor (n = 3) |
276 (271 to 278) |
- |
2.4 (2.4 to 2.4) |
8.8 (8.7 to 8.9) |
5 MBq 211At-BR96 |
|
|
|
|
Tumor (n = 6) |
259 (247 to 266) |
371 (176 to 520) |
5.0 (4.9 to 5.1) |
19.2 (18.3 to 19.9) |
Non-tumor (n = 3) | 264 (259 to 267) | - | 4.8 (4.6 to 4.9) | 18.0 (17.5 to 18.3) |
IA, injected activity.