FIG. 2.

Developmental exposure to BPA alters overall lung inflammation. Adult female (N = 5–6) or male offspring (N = 3–6) of BPA exposed or vehicle control dams were sensitized (i.t.) with OVA alone or OVA + LPS prior to aerosol challenge. Scoring was performed by three independent scientists, using coded slides. Representative images are from H&E-stained lung tissue at 40× magnification (A, C) and depict the cumulative histopathological assessment. Graphs (B, D) present the mean inflammation scores for each group (error bars = SEM). An asterisk (*) indicates p ≤ 0.05 when mean values from the same sensitization/challenge group, but different BPA exposure groups, were compared.