Table 2.
Significantly expressed Tm3 genes possessing strain-specific SNPs and a designated biological (KEGG) pathway
| Gene | KEGG designated pathway | SNP no. | Gene | KEGG designated pathway | SNP no. |
|---|---|---|---|---|---|
|
Vav3 |
Chemokine signalling pathway |
2047 |
Fcgr1 |
Fc gamma R-mediated phagocytosis |
18 |
| |
Fc gamma R-mediated phagocytosis |
|
|
Hematopoietic cell lineage |
|
| |
Focal adhesion |
|
|
Leishmaniasis |
|
| |
Leukocyte transendothelial migration |
|
|
Phagosome |
|
| |
T cell receptor signalling pathway |
|
|
Systemic lupus erythematosus |
|
| |
B cell receptor signalling pathway |
|
Prpf38b |
Spliceosome |
9 |
| |
Regulation of actin cytoskeleton |
|
|
|
|
|
Hmgcs2 |
Butanoate metabolism |
134 |
Vcam1 |
Cell adhesion moleculaes (CAMs) |
8 |
| |
Metabolic pathways |
|
|
Leukocyte transendothelial migration |
|
| |
Synthesis and degradation of ketone |
|
|
Malaria |
|
| |
Terpenoid backbone biosynthesis |
|
Cdc14a |
Cell cycle |
7 |
| |
Valine, leuckine and isoleucine degradation |
|
|
|
|
|
Ctss |
Antigen processing and presentation |
120 |
Dbt |
Metabolic pathways |
2 |
| |
Lysosome |
|
|
Valine, leucine and isoleucine degradation |
|
| |
Phagosome |
|
|
|
|
|
Ap4b1 |
Lysosome |
92 |
Gstm7 |
Drug metabolism – cytochrome P450 |
2 |
|
Rorc |
Circadian rhythm |
76 |
|
Glutathione metabolism |
|
| |
|
|
|
Metabolism of xenobiotics by cytochrome p450 |
|
|
Gstm3 |
Drug metabolism – cytochrome P450 |
73 |
Hsd3b6 |
Metabolic pathways |
2 |
| |
Glutathione metabolism |
|
|
Steroid hormone biosynthesis |
|
| |
Metabolism of xenobiotcis by cytochrome P450 |
|
|
|
|
|
Dpyd |
Beta-Alanin metabolism |
24 |
Fmo5 |
Drug metabolism – cytochrome p450 |
1 |
| |
Drug metabolism – other enzymes |
|
|
|
|
| |
Metabolic pathways |
|
Gstm6 |
Drug metabolism – cytochrome p450 |
1 |
| |
Pantothenate and CoA biosynthesis |
|
|
|
|
| Pyrimidine metabolism | Hist2h2be | Systemic lupus erythematosus | 1 |