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. 2013 Mar 21;54(3):2076–2086. doi: 10.1167/iovs.12-11102

Table 5. .

Validation of the Most Significantly Associated SNPs in a Previously Genotyped Independent Cohort

Base Pair Location
SNP
Gene Location
Qualitative SPH P Value
Quantitative SPH P Value
69425930 rs3803036 Coding nonsyn. in PTPRR 0.73 0.15
71970854 rs1520562 >600 kb from nearest gene 0.075 0.024
76672201 rs1358228 76 kb upstream of NAV3 0.17 0.32
78976016 rs7315130 >100 kb from nearest gene 0.86 0.97
80351222 rs17306116 Intronic PPFIA2 0.82 0.99

The most significantly associated SNPs from our data not included in this table were not present in the independent data set. Base pairs are based on human genome build 36.2, chromosome 12. Methods of this testing and cohort information have been previously published.29