Table 5.
Cognitive testing data
| CRFS cases | Controls | ||||
|---|---|---|---|---|---|
| Variable | Mean | SD | Mean | SD | p Value |
| DMS percentage correct (all delays) | 81.78 | 11.63 | 84.83 | 11.43 | 0.17 |
| DMS mean correct latency (ms) | 3528 | 1151 | 3707 | 1416 | 0.48 |
| IED stages completed | 7.40 | 2.40 | 7.33 | 2.40 | 0.89 |
| IED total errors (adjusted) | 50.37 | 51.71 | 52.65 | 53.43 | 0.83 |
| MTS mean correct reaction time | 3515 | 1143 | 3156 | 1137 | 0.10 |
| MTS per cent correct | 94.32 | 6.10 | 93.38 | 5.78 | 0.41 |
| PAL stages completed | 3.40 | 0.78 | 3.50 | 0.86 | 0.76 |
| PAL total errors (adjusted) | 95.60 | 29.67 | 92.90 | 32.05 | 0.65 |
| PAL total trials (adjusted) | 20.47 | 6.78 | 20.09 | 7.29 | 0.78 |
| RVP A' (scores between 0 and 1) | 0.87 | 0.06 | 0.89 | 0.07 | 0.15 |
| RVP total correct rejections | 236.69 | 25.83 | 245.53 | 14.95 | 0.02 |
| RVP mean latency (ms) | 533 | 127 | 468 | 126 | 0.009 |
| VRM free recall – total correct | 7.00 | 1.77 | 7.75 | 1.75 | 0.03 |
| VRM recognition – total correct | 22.78 | 1.38 | 23.06 | 1.42 | 0.3 |
| AGN mean correct latency (ms) | 532 | 71 | 517 | 61 | 0.24 |
| AGN total omissions | 5.17 | 1.99 | 4.57 | 1.78 | 0.64 |
| AGN total commissions | 7.76 | 1.75 | 6.57 | 1.72 | 0.03 |
AGN: Affective Go No-go (information processing and reaction time). There are three outcomes: mean correct latency (time taken for a correct response), total omissions which are incorrect responses to a target word (ie, the subject not pressing the button when they should have) and total commissions which are the total number of incorrect responses to the distracter words (ie, pressing the button inappropriately).
DMS: Delayed Matching to Sample (memory and reaction time). There are two outcomes: overall correct responses (percentage) and latency of response (time taken to make correct response).
IED: Intra-Extra Dimensional Set Shift (rule acquisition and reversal). There are two outcomes: stages complete is the number successfully completed and total errors (adjusted for stages) is a measure of the efficiency of completing the test.
MTS: Match To Sample (matching test with speed/accuracy trade off). There are two outcomes: overall correct responses (percentage) and latency of response (time taken to make correct response).
PAL: Paired Associates Learning (visual memory and new learning). There are two outcomes: total errors (adjusted from stages completed) and total trials (number of attempts needed to complete task adjusted for early abortion).
RVP: Rapid Visual Information Processing (sensitive measure of general performance). There are three outcomes: A' is a probability score of how good a participant is at detecting sequences, correct rejection is the number of times a false sequence is ignored between correct ones and the mean latency is the time of response between the end of a sequence and the participant pressing the button.
VRM: Verbal Recognition Memory (verbal information under free recall and forced choice recognitions). There are two outcomes: free recall number of correct words and a forced choice correct total (yes/no as to whether word was in the original list).
CRFS, cancer-related fatigue syndrome.