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. 2013 Jan 11;32(1):3. doi: 10.1186/1756-9966-32-3

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Copyright © 2013 Liao et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Prognostic significance of peritumoral IL-17RE, intratumoral IL-17RE and IL-17. High density of peritumoral IL-17RE (a and b), intratumoral IL-17RE (c and d) and intratumoral IL-17 (g and h) were related to decreased overall survival (OS, a, c and g) and time to recurrence (TTR, b, d and h). Combination of intratumoral IL-17RE and IL-17 was also associated with OS (i) and TTR (j). I: both low density; II: low IL-17RE but high IL-17 density; III: high IL-17RE but low IL-17 density; and IV: both high density. Peritumoral IL-17 (e and f) showed no predictive value for OS (e) and TTR (f).