Table 1.

Criteria for risk classification in acute myeloid leukemia

	South West Oncology Group( 17 ) Criteria	Medical Research Council( 18 ) Criteria identical to South West Oncology Group except
	t(15;17) + any other abnormality
Favorable	inv(16)/t(16;16)/del(16q) + any other abnormality
	t(8;21) without del(9q) or complex karyotype	t(8;21) + any other abnormality
	+8, -Y, +6, del(12p)	abnormal 11q23
	normal karyotype	del(9q), del(7q) - without other abnormalities
Intermediate		complex karyotype (≥ 3 abnormalities but < 5 abnormalities)
		all significant abnormalities
		unknown prognosis
Unfavorable	-5/del(5q), -7/del(7q)
	t(8;21) with del(9q)
	inv(3q), abnormal 11q23, 20q.
	21q, del(9q), t(6;9)
	T(9:22), abnormal 17p
	complex karyotypes (≥ 3 abnormalities)	complex karyotypes (≥ 5 abnormalities)
Unknown	All other clonal anomalies with < 3 abnormalities