Table 1.
Hepatoprotective effect of HCIF on CCl4-induced toxicity in rats
| GOT (IU/L) | GPT (IU/L) | ALP (IU/L) | LDH (IU/L) | |
|---|---|---|---|---|
| Untreated |
41.4 ± 5.9 |
14.2 ± 0.4 |
161.6 ± 16.7 |
720.4 ± 51.1 |
| CCl4-treated control |
197.3 ± 10.4# |
148.6 ± 9.6# |
330.5 ± 36.3# |
2516.2 ± 439.4# |
| Silymarin + CCl4 (50 mg/kg) |
71.5 ± 4.9*** |
60.5 ± 6.8*** |
202.3 ± 34.2*** |
1122.1 ± 135.5*** |
| HCIF50 + CCl4 (50 mg/kg) | 99.5 ± 7.8*** | 66.1 ± 14.0*** | 228.7 ± 26.3*** | 1368.6 ± 144.3*** |
Serum GOT, GPT, ALP and LDH levels were determined by commercial kits. Each value is the mean ± SD; n = 9 rats. #P < 0.001, significantly different from the untreated group. ***P < 0.01, significantly different from the CCl4-treated control group.