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. Author manuscript; available in PMC: 2013 Apr 9.
Published in final edited form as: Bioconjug Chem. 2009 Jun 24;20(8):1634–1642. doi: 10.1021/bc9001954

Figure 2.

Figure 2

The competitive binding curve (A) of RGD-Lys-(Arg11)CCMSH in B16/F1 melanoma cells. The IC50 value of RGD-Lys-(Arg11)CCMSH was 2.1 nM; Cellular internalization (B) and efflux (C) of 99mTc-RGD-Lys-(Arg11)CCMSH in B16/F1 melanoma cells at 25 °C. Total bound radioactivity (◆), internalized activity (■), cell membrane activity (▲), and cell culture medium activity (●) were presented as counts per minute (cpm).