Table 2. Metabolic characteristics and food intake of HFD and STD fed C57Bl/6 mice.

		Food Intake	Weight	Fasting Glucose
		(g/day)	(g)	(mg/dl)
STD	Baseline	3.35±0.20	18.7±1.9	73±8
	w11	4.29±1.10	27.9±4.4	82±16
	w11 Ad-GFP	n.a.	28.3±2.7	84.3±9.2
	w11 Ad-D4	n.a.	28.5±1.7	82.9±13.1
HFD	Baseline	2.97±0.61	18.3±2.2	68±10
	w11	4.00±0.90	40.4±5.2b	120±15a
	w11 Ad-GFP	n.a.	41.2±1.9c	117±22c
	w11 Ad-D4	n.a.	41.6±2.3d	102±13e

Mice were analysed as described under Materials and Methods. Data are the means ± SEM of determinations in 12 STD and 12 HFD fed C57Bl/6 mice on the following conditions: baseline, upon 11 week of diet (w11), upon w11 treated with Ad-GFP and upon w11 treated with Ad-D4. HFD w11 vs. STD w11 mice;

^a p<0.01 and

^b p<0.001; HFD w11 Ad-GFP vs. STD w11 mice;

^c p<0.001; HFD w11 Ad-D4 vs. STD w11 mice;

^d p<0.001; HFD w11 Ad-D4 vs. HFD w11 Ad-GFP mice;

^e p<0.001; n.a., not available.