Table 4.
Characteristics of the main Finnish Diabetes Risk Score (FINDRISC) cut-off points for screening-detected type 2 diabetes and glucose abnormalities (diabetes and pre-diabetes), classified by glucose and hemoglobin (Hb)A1c diagnostic criteria.
| Cut-off values | n (%) | Diabetesa | Glucose abnormalitiesa | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | Sensitivity | Specificity | PPV | NPV | ||
| Diagnostic classification by the WHO criteria (2-hour plasma glucose) | |||||||||
| 6 | 31 (1.8) | 100.0 | 4.3 | 9.6 | 100.0 | 99.3 | 5.4 | 32.5 | 94.0 |
| 10 | 111 (6.5) | 94.9 | 19.7 | 11.7 | 97.5 | 90.9 | 22.6 | 35.0 | 84.4 |
| 13 | 166 (9.7) | 81.0 | 42.1 | 12.5 | 95.6 | 73.2 | 46.0 | 38.3 | 78.9 |
| 14 | 139 (8.1) | 75.9 | 52.3 | 13.9 | 95.5 | 65.8 | 56.7 | 41.1 | 78.4 |
| 15 | 156 (9.1) | 69.6 | 60.6 | 15.2 | 95.1 | 59.7 | 65.8 | 44.4 | 78.1 |
| Diagnostic classification by the ADA criteria (fasting plasma glucose) | |||||||||
| 6 | 31 (1.8) | 100.0 | 4.0 | 3.2 | 100.0 | 99.2 | 5.1 | 29.2 | 94.0 |
| 10 | 111 (6.5) | 100.0 | 18.9 | 3.8 | 100.0 | 92.6 | 22.7 | 32.1 | 88.5 |
| 13 | 166 (9.7) | 84.9 | 40.7 | 4.4 | 98.8 | 75.3 | 46.0 | 35.5 | 82.5 |
| 14 | 139 (8.1) | 75.5 | 50.5 | 4.6 | 98.5 | 68.0 | 56.6 | 38.3 | 81.8 |
| 15 | 156 (9.1) | 67.9 | 58.6 | 5.0 | 98.3 | 61.6 | 65.4 | 41.4 | 81.2 |
| Diagnostic classification by the HbA1c-based criteria | |||||||||
| 6 | 31 (1.8) | 98.4 | 4.0 | 3.7 | 98.5 | 97.1 | 4.3 | 29.0 | 79.1 |
| 10 | 111 (6.5) | 93.5 | 18.8 | 4.2 | 98.7 | 83.9 | 19.2 | 29.5 | 74.8 |
| 13 | 166 (9.7) | 77.4 | 40.6 | 4.7 | 98.0 | 62.3 | 40.9 | 29.8 | 73.0 |
| 14 | 139 (8.1) | 74.2 | 50.5 | 5.3 | 98.1 | 54.4 | 51.3 | 31.0 | 73.6 |
| 15 | 156 (9.1) | 69.4 | 58.8 | 5.9 | 98.1 | 46.6 | 59.5 | 31.7 | 73.5 |
ADA, American Diabetic Association; Hb, hemoglobin; NPV, negative predictive value; PPV, positive predictive value.
aData on sensitivity, specificity, PPV and NPV are percentages.