Table 1.

Voltage-dependent properties of Ca²⁺ channels in DRGs from naive and CFA-treated mice

	Naive	CFA
Activation
Gmax	308 ± 51	288 ± 41
Slope	6.1 ± 0.8	6.5 ± 0.9
V1/2	−25.2 ± 1.0	−25.6 ± 1.0
Inactivation
Slope	16.5 ± 2.5	9.9 ± 0.9
V1/2	−13.2 ± 4.8	−14.0 ± 1.3
Constitutive Inhibition
	1.00 ± 0.02	1.01 ± 0.02
GABAB inhibition (%)
	42.4 ± 3.2	45.5 ± 4.3

Patch-clamp recordings under voltage-clamp conditions were used to examine Ca²⁺ channel function in medium to large-sized L4-L6 DRG neurons from naive (61± 5 pF) and CFA (64 ± 6 pF) treated mice. CFA did not alter the maximal current amplitude (G_max; pA/pF; F_{(13, 234)} = 0.21), the kinetics of channel activation (p > 0.05, F_(13,126) = 0.04), steady-state inactivation ( p > 0.05, F_(12,2040) = 1.3), constitutive current inhibition (p > 0.05, t₁₄ = 0.89) or GABA_B inhibition of the Ca²⁺ channels (p > 0.05, t₁₂ = 0.59). V_1/2 = half-maximal potential of the conductance-voltage relationship.