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. 2013 Apr 9;8(4):e60635. doi: 10.1371/journal.pone.0060635

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© 2013 Centola et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The MBDA score algorithm uses an equation analogous to that for the DAS28-CRP, with biomarkers used to predict the Swollen Joint Count (SJC28), Tender Joint Count (TJC28), and Patient Global Assessment (PG) components of the equation. The Venn diagram lists the MBDA score biomarkers used to predict each MBDA score component. YKL-40, human cartilage glycoprotein-39; IL-6, interleukin-6; SAA, serum amyloid A; EGF, epidermal growth factor; TNF-RI, tumor necrosis factor receptor 1; VEGF-A, vascular endothelial growth factor-A; MMP, matrix metalloproteinase.