Table 1.
Top hits in -TNF and +TNF screens.
| -TNF screen | ||||
|---|---|---|---|---|
| miRNA | Seed sequence | Fold change | Z-score | P-value |
| hsa-miR-517c | UCGUGCA | 126.3 | 4.8 | 0.015 |
| hsa-miR-517a | UCGUGCA | 86.2 | 4.4 | 0.015 |
| hsa-miR-544 | UUCUGCA | 37.9 | 3.6 | 0.016 |
| hsa-miR-337 | CCAGCUC | 38.0 | 3.6 | 0.016 |
| hsa-miR-452* | CAGUCUC | 19.7 | 3.0 | 0.018 |
| hsa-miR-326 | CUCUGGG | 18.8 | 2.9 | 0.018 |
| hsa-miR-184 | GGACGGA | 19.0 | 2.8 | 0.019 |
| hsa-miR-34b | AGGCAGU | 16.1 | 2.7 | 0.019 |
| hsa-miR-483 | CACUCCU | 12.8 | 2.5 | 0.019 |
| +TNF screen | ||||
| miRNA | Seed sequence | Fold change | Z-score | P-value |
| hsa-miR-124a | UAAGGCA | -82.8 | -4.6 | 0.015 |
| hsa-miR-452* | CAGUCUC | 4.5 | 1.6 | 0.015 |
| hsa-miR-483 | CACUCCU | 6.1 | 1.9 | 0.015 |
| hsa-miR-506 | AAGGCAC | -22.8 | -3.3 | 0.016 |
| hsa-miR-345 | GCUGACU | -22.9 | -3.3 | 0.016 |
| hsa-miR-24 | GGCUCAG | -23.7 | -3.3 | 0.016 |
| hsa-miR-375 | UUGUUCG | -21.2 | -3.2 | 0.016 |
| hsa-miR-141 | AACACUG | 3.9 | 1.4 | 0.018 |
| hsa-miR-130a | AGUGCAA | 3.8 | 1.4 | 0.018 |
| hsa-miR-491 | GUGGGGA | -15.3 | -2.9 | 0.018 |
| hsa-miR-30a-3p | UUUCAGU | 3.9 | 1.4 | 0.018 |
| hsa-miR-489 | GUGACAU | -13.7 | -2.7 | 0.018 |
| hsa-miR-125b | CCCUGAG | 3.5 | 1.3 | 0.020 |
| hsa-miR-200b | AAUACUG | 3.8 | 1.4 | 0.020 |
| hsa-miR-210 | UGUGCGU | -9.8 | -2.4 | 0.020 |
miRNA, microRNA; TNF, tumor necrosis factor.