Table 2. Antibiotic resistance levels of serogroup 6 isolates from IPD among German children and adults.
serotype | n = | PEN I+R (%) | CLA R (%) | CLI R(%) | TET R (%) | MDR(%) |
children | ||||||
6A | 116 | 5 (4.3) | 10 (8.6) | 2 (1.7) | 5 (4.3) | 2 (1.7) |
6B | 204 | 31 (15.2) | 57 (27.9) | 44 (21.6) | 46 (22.5) | 42 (20.6) |
6C | 15 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
SG6 | 335 | 38 (11.3) | 67 (20.0) | 46 (13.7) | 51 (15.2) | 44 (13.1%) |
all serotypes | 3508 | 257 (7.3) | 755 (21.5) | 217 (6.2) | 280 (8.0) | 190 (5.4%) |
adults | ||||||
6A | 432 | 21 (4.9) | 44 (10.2) | 13 (3.0) | 25 (5.8) | 10 (2.3) |
6B | 354 | 63 (17.8) | 110 (31.1) | 91 (25.7) | 94 (26.6) | 87 (24.6) |
6C | 270 | 17 (6.3) | 17 (6.3) | 10 (3.7) | 13 (4.8) | 10 (3.7) |
6D | 4 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
SG6 | 1062 | 101 (9.5) | 171 (16.1) | 113 (10.6) | 127 (12.0) | 107 (10.1%) |
all serotypes | 15791 | 953 (6.0) | 1857 (11.8) | 784 (5.0) | 1098 (7.0) | 714 (4.5%) |
PEN: penicillin (breakpoints S, I, R (µg/ml ): ≤0.06, 0.12–1, ≥2), CLA: clarithromycin (breakpoints S, I, R (µg/ml ): ≤0.25, 0.5, ≥1), CLI: clindamycin (breakpoints S, I, R (µg/ml ): ≤0.25, 0.5, ≥1), TET: tetracycline (breakpoints S, I, R (µg/ml ): ≤2, 4, ≥8), MDR: multi drug resistant (resistant to ≥3 classes of antibiotics).