Table 4. KEGG pathways with significant association with genes differentially expressed in female and male rat choroid plexus.
Females | Males | |||||||
Up-regulated | Down-regulated | Up-regulated | Down-regulated | |||||
Kegg pathways | Number of genes | P-value | Number of genes | P-value | Number of genes | P-value | Number of genes | P-value |
Olfactory transduction | 102 | 3.1E-12 | 282 | 1.7E-99 | 42 | 5.1E-5 | ||
Primary immunodeficiency | 7 | 8.5E-3 | ||||||
Steroid hormone biosynthesis | 7 | 2.6E-2 | 15 | 8.8E-6 | 5 | 1.7E-2 | ||
Taste transduction | 7 | 4.6E-2 | ||||||
Maturity onset diabetes of the young | 6 | 1.1E-2 | ||||||
Retinol metabolism | 18 | 6.4E-6 | ||||||
Drug metabolism | 16 | 1.1E-3 | ||||||
Metabolism of xenobiotics by cytochrome P450 | 15 | 4.9E-4 | ||||||
Pentose and glucuronate interconversions | 6 | 7.1E-3 | ||||||
Ascorbate and aldarate metabolism | 6 | 1.3E-2 | ||||||
Circadian rhythm | 3 | 3.0E-3 |