Table I. Patient, donor, and graft characteristics.
Pt | Age at HCT (yrs) |
Ethnicity | Time from dx to HCT (yrs) |
Abn Cyto- genetics |
RBC/Platelet transfusions |
Androgen therapy |
Donor status to patient |
HLA Matching | ABO Pt/ Donor |
CMV status Pt / Donor |
CD34 cell dose/kg (106) |
TNC dose/kg (108) |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Class I | Class II | |||||||||||||||
Patient Donor | ||||||||||||||||
A | B | C | DRB1 | DQ | ||||||||||||
1 | 13 | Brazilian-Mixed | 2.5 | No | 50/>70(ferritin 13,000) | Yes | Half-sib | 02CMZW/31CNSK | 44AJVH/5201 | 05ANJN/0102 | 040701/160201 | 0301/0301 | B+/B+ | +/+ | 2.21 | 5.27 |
02CMZW/31CNSK | 35AEYZ/5201 | 03CRCV/0102 | 1402/160201 | 0301/0301 | ||||||||||||
2 | 6 | Hispanic | 2.5 | No | 0/1 | No | Mother | 11AGWS/11AGWS | 27AHUV/35HNH | 01FJJ/12NP | 0404/0408 | 03BG/0304 | O−/O− | +/+ | 3.69 | 4.46 |
11AGWS/02AGSM | 35HNH/35ASNB | 12NP/04CZYV | 0408/1602 | 0304/03CFTD | ||||||||||||
3 | 11 | Brazilian-Mixed | 1.5 | No | 5/3 (ferritin 1000) | Yes (significant virilization) | Cousin | 1101/3001 | 3501g/5501 | 0303/20N /0401g | 0103/0301 | 0501/0201 | AB+/O+ | +/+ | 4.41 | 5.38 |
0301/3001 | 3501g/5501 | 0303/20N /0401g | 0103/0301 | 0501/0201 |