Skip to main content
. Author manuscript; available in PMC: 2013 Apr 10.
Published in final edited form as: Adv Mater. 2011 Sep 28;23(42):4908–4912. doi: 10.1002/adma.201102677

Figure 5. Analysis of A30 decrosslinking of DPPC:DPPA:DSPE-PAA-A15 microbubbles pre-crosslinked with T30.

Figure 5

(a) Schematic of re-activation through addition of longer oligonucleotide (A30) complementary to crosslinking strand (T30). (b,d) Bright field and green fluorescence microscopy images of microbubbles crosslinked with FAM-T30. (c,e) Microscopy images of same sample after addition of A30. (f) Comparison of oscillating microbubble fraction for uncrosslinked (A15), crosslinked (T30), and decrosslinked (A30) microbubbles. (g) Contrast enhanced ultrasound image of crosslinked microbubbles in phantom. (h) Contrast enhanced ultrasound image of same suspension after addition of A30.