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. 2013 Apr 10;3:1647. doi: 10.1038/srep01647

Figure 1. A small component of the drug-target protein network consisting of 11 drugs (hexagons) interacting with five disease-gene products corresponding to cardivascular disorder class.

Figure 1

Although 11 drugs interact with these proteins, only three drugs (red hexagons) are required to control the system simultaneously. Drugs belonging to the DS are indicated in red. These three drugs are called the cover set (or dominating set DS) of the network. Interactions between the drugs from the DS and the disease-gene products are represented as wavy red arrows.